Deep infection in tumor endoprosthesis around the knee: a multi-institutional study by the Japanese musculoskeletal oncology group
نویسندگان
چکیده
BACKGROUND The incidence of endoprosthesis failure has been well studied, but few studies have described the clinical characteristics of deep infection in tumor prostheses. This study aimed to analyze the characteristics of deep infection in tumor endoprostheses around the knee. METHODS We analyzed clinical data of 57 patients with deep infections involving tumor endoprostheses around the knee enrolled from the Japanese Musculoskeletal Oncology Group. Profile of clinical presentation including time between surgery and infection, initial symptoms/blood tests and microbial cultures was evaluated. In addition pre-, intra-, and postoperative clinical factors influencing clinical presentation and treatment outcomes of infections were analyzed. RESULTS Mean interval between the initial operation and diagnosis was 13 months, and mean time required for infection control was 12 months. The most common pathogen was Staphylococcus. Infection control rates were significantly higher when prostheses were removed rather than salvaged. Ten-year prosthesis survival and limb salvage rates were 41.6% and 75.6%, respectively. Analysis of underlying clinical factors suggested that soft-tissue condition significantly influenced the duration of the infection control period and likelihood of limb salvage. CONCLUSIONS Infection control is a prolonged process. Deep infection frequently results in amputation or prosthesis loss. Intensive analysis of clinical characteristics may aid infection control.
منابع مشابه
Deep infection in tumor endoprosthesis around the knee: characteristics of clinical presentation, status of infection control, and prosthesis/limb survival-a multi institutional study by the Japanese Musculoskeletal Oncology Group-
متن کامل
Early Functional Outcome of Resection and Endoprosthesis Replacement for Primary Tumor around the Knee
UNLABELLED We evaluated functional outcomes for patients who underwent surgery for resection and endoprosthesis replacement for primary tumours around the knee. We used the Musculoskeletal Tumour Society Scoring System (MSTS) for functional evaluations to compare differences between distal femur (DF) and proximal tibia (PT) placements. The study sample included 34 cases of distal femur and 20 c...
متن کاملThe Effect of Knee Joint Muscles Deep Dry Needling on Pain and Function in Patients After Total Knee Arthroplasty
Objective Osteoarthritis is one of the most common knee joint diseases. It is a multifactorial, inflammatory, and destructive disorder of the joint that involves the synovial tissues and joint cartilage and causes permanent pain, functional limitations, and a decrease in patients’ quality of life. In advanced cases of the disease, total knee arthroplasty is performed to reduce pain and improve ...
متن کاملA Comparison of the Postoperative Complications between Two Drainage Methods after Total Knee Arthroplasty
Background: The role of wound drainage after total knee arthroplasty is still considered controversial as althoughclosed drainage systems have been believed to be effective in decreasing the post-operative complications, they couldalso facilitate the bleeding and increase the rate of transfusion and infection. We have conducted the current study tocompare the outcomes superficial subcutaneous, ...
متن کاملTreatment of osteosarcoma around the knee in skeletally immature patients
Limb sparing surgery in growing young patients with malignant tumors is difficult as invasion of the physis by the tumor or surgical resection through the metaphysis may cause significant limb discrepancy following surgery. At present, hinged tumor prosthesis or biological reconstructions are the main methods following tumor resection in these patients. The aim of the present study was to asses...
متن کامل